Rune recipes

5 slots: Rebirth Rune + Prismatic Rune + Ward Rune + Toxic Rune + Soul Rune

Head start: Ward Rune in slot 3 (area 70–100)

Chaos Orb ×3

5 slots: Adaptive Rune + Oath Rune + Death Rune + Rebirth Rune + Tempest Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Death Rune in slot 3 (area 70–100)

Conductive Runes

5 slots: Cyclonic Rune + Lightning Rune + 2× Vision Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100), Lightning Rune in slot 2 (area 70–100)

Courtesan Mannan's Rune of Cruelty

5 slots: Bloodletting Rune + Cold Rune + Toxic Rune + Time Rune + Volcanic Rune

Head start: Cold Rune in slot 2 (area 65–100)

Craiceann's Rune of Recovery

5 slots: Death Rune + Tidal Rune + Soul Rune + Time Rune + Rage Rune

Head start: Tidal Rune in slot 2 (area 65–100)

Craiceann's Rune of Warding

5 slots: Life Rune + Tidal Rune + Cold Rune + Time Rune + Ward Rune

Head start: Tidal Rune in slot 2 (area 65–100)

Detonate Living

5 slots: Cyclonic Rune + Volcanic Rune + Celestial Rune + Fire Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100), Fire Rune in slot 4 (area 70–100)

Divine Orb ×2

5 slots: Death Rune + Soul Rune + Power Rune + Life Rune + Vision Rune

Head start: Power Rune in slot 3 (area 55–100)

Eternal March

5 slots: Cyclonic Rune + Prismatic Rune + Protective Rune + Rebirth Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100)

Farrul's Rune of Grace

5 slots: Momentum Rune + Bloodletting Rune + Adaptive Rune + Time Rune + Life Rune

Head start: Momentum Rune in slot 1 (area 70–100), Bloodletting Rune in slot 2 (area 65–100)

Farrul's Rune of the Hunt

5 slots: Vision Rune + Bloodletting Rune + Bond Rune + Time Rune + Rage Rune

Head start: Bloodletting Rune in slot 2 (area 65–100), Bond Rune in slot 3 (area 70–100)

Fenumus' Rune of Agony

5 slots: Volcanic Rune + Toxic Rune + Adaptive Rune + Time Rune + Vision Rune

Head start: Toxic Rune in slot 2 (area 65–100)

Fenumus' Rune of Draining

5 slots: Death Rune + Toxic Rune + Cold Rune + Time Rune + Arcane Rune

Head start: Toxic Rune in slot 2 (area 65–100)

Fenumus' Rune of Spinning

5 slots: Momentum Rune + Toxic Rune + Tempest Rune + Time Rune + Protective Rune

Head start: Momentum Rune in slot 1 (area 70–100), Toxic Rune in slot 2 (area 65–100)

Fragments Of The Past

5 slots: Cyclonic Rune + Tempest Rune + Lightning Rune + Toxic Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100)

Frostflame Nova

5 slots: Cyclonic Rune + Lightning Rune + Fire Rune + Momentum Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100), Lightning Rune in slot 2 (area 70–100)

Greater Orb of Augmentation ×3

5 slots: Rebirth Rune + Arcane Rune + Electrocuting Rune + Adaptive Rune + Bond Rune

Head start: Arcane Rune in slot 2 (area 70–100), Electrocuting Rune in slot 3 (area 65–100), Adaptive Rune in slot 4 (area 70–100), Bond Rune in slot 5 (area 44–100)

Greater Orb of Transmutation ×3

5 slots: Volcanic Rune + Fire Rune + Cold Rune + Adaptive Rune + Bond Rune

Head start: Fire Rune in slot 2 (area 70–100), Adaptive Rune in slot 4 (area 70–100), Bond Rune in slot 5 (area 44–100)

Grim Pillars

5 slots: Volcanic Rune + Earth Rune + Ward Rune + Momentum Rune + Soul Rune

Head start: Ward Rune in slot 3 (area 70–100)

Lady Hestra's Rune of Winter

5 slots: Tidal Rune + Cold Rune + Cyclonic Rune + Time Rune + Tempest Rune

Head start: Cold Rune in slot 2 (area 65–100), Cyclonic Rune in slot 3 (area 70–100)

Masterwork Rune

5 slots: Prismatic Rune + Wisdom Rune + Sky Rune + Arcane Rune + Rebirth Rune

Head start: Prismatic Rune in slot 1 (area 65–100), Sky Rune in slot 3 (area 70–100), Arcane Rune in slot 4 (area 55–100)

Mystic Alloy

5 slots: Adaptive Rune + Rebirth Rune + Time Rune + Arcane Rune + Electrocuting Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Rebirth Rune in slot 2 (area 44–100), Arcane Rune in slot 4 (area 55–100)

Discover this recipe in Act 2

Orb of Chance

5 slots: Celestial Rune + Time Rune + Rage Rune + Bloodletting Rune + Rebirth Rune

Head start: Celestial Rune in slot 1 (area 65–100), Bloodletting Rune in slot 4 (area 70–100)

Perfect Jeweller's Orb

5 slots: Prismatic Rune + Adaptive Rune + Death Rune + Life Rune + Volcanic Rune

Head start: Prismatic Rune in slot 1 (area 65–100), Death Rune in slot 3 (area 70–100)

Perfect Orb of Augmentation

5 slots: Adaptive Rune + Time Rune + Sky Rune + Tidal Rune + Rebirth Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Sky Rune in slot 3 (area 70–100)

Perfect Orb of Transmutation

5 slots: Adaptive Rune + Death Rune + Sky Rune + Oath Rune + Celestial Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Sky Rune in slot 3 (area 70–100)

Powered by Verisium

5 slots: Arcane Rune + Earth Rune + Ward Rune + Vision Rune + Soul Rune

Head start: Ward Rune in slot 3 (area 70–100)

Prismatic Alloy

5 slots: Prismatic Rune + Rebirth Rune + Adaptive Rune + Opulent Rune + Bond Rune

Head start: Prismatic Rune in slot 1 (area 65–100), Rebirth Rune in slot 2 (area 44–100), Bond Rune in slot 5 (area 44–100)

Discover this recipe in Act 2

Rare Unique Item

Uniques

5 slots: Celestial Rune + Wisdom Rune + Protective Rune + Rage Rune + Bond Rune

Head start: Celestial Rune in slot 1 (area 65–100), Bond Rune in slot 5 (area 44–100)

Remnants of Kalguur

5 slots: Sky Rune + Tempest Rune + Ward Rune + Lightning Rune + Soul Rune

Head start: Ward Rune in slot 3 (area 70–100)

Repulsion

5 slots: Cyclonic Rune + Earth Rune + Protective Rune + Lightning Rune + Life Rune

Head start: Cyclonic Rune in slot 1 (area 70–100)

Saqawal's Rune of Erosion

5 slots: Rebirth Rune + Sky Rune + Vision Rune + Time Rune + Toxic Rune

Head start: Sky Rune in slot 2 (area 65–100)

Saqawal's Rune of Memory

5 slots: Arcane Rune + Sky Rune + Soul Rune + Time Rune + Moon Rune

Head start: Sky Rune in slot 2 (area 65–100)

Saqawal's Rune of the Sky

5 slots: Rebirth Rune + Sky Rune + Bloodletting Rune + Time Rune + Volcanic Rune

Head start: Sky Rune in slot 2 (area 65–100)

Thane Girt's Rune of Wildness

5 slots: 2× Rage Rune + Bond Rune + Time Rune + Volcanic Rune

Head start: Bond Rune in slot 2 (area 65–100)

Thane Grannell's Rune of Mastery

5 slots: Electrocuting Rune + Bond Rune + Tidal Rune + Time Rune + Prismatic Rune

Head start: Bond Rune in slot 2 (area 65–100)

Thane Leld's Rune of Spring

5 slots: Lightning Rune + Bond Rune + Volcanic Rune + Time Rune + Electrocuting Rune

Head start: Lightning Rune in slot 1 (area 70–100), Bond Rune in slot 2 (area 65–100)

Thane Myrk's Rune of Summer

5 slots: Fire Rune + Bond Rune + Rage Rune + Time Rune + Death Rune

Head start: Fire Rune in slot 1 (area 70–100), Bond Rune in slot 2 (area 65–100)

Thaumaturgic Flux (Level 19)

5 slots: Momentum Rune + Earth Rune + Ward Rune + Bloodletting Rune + Arcane Rune

Head start: Momentum Rune in slot 1 (area 70–100), Ward Rune in slot 3 (area 70–100), Bloodletting Rune in slot 4 (area 70–100)

The Greatwolf's Rune of Claws

5 slots: Bloodletting Rune + Rage Rune + Momentum Rune + Time Rune + Toxic Rune

Head start: Rage Rune in slot 2 (area 65–100), Momentum Rune in slot 3 (area 70–100)

The Greatwolf's Rune of Willpower

5 slots: Tidal Rune + Rage Rune + Toxic Rune + Time Rune + Momentum Rune

Head start: Rage Rune in slot 2 (area 65–100)

Uncut Skill Gem (Level 19)

5 slots: Momentum Rune + Fire Rune + Electrocuting Rune + Cold Rune + Prismatic Rune

Head start: Momentum Rune in slot 1 (area 70–100), Fire Rune in slot 2 (area 70–100), Electrocuting Rune in slot 3 (area 65–100)

Uncut Spirit Gem (Level 19)

5 slots: Momentum Rune + Arcane Rune + Prismatic Rune + Life Rune + Tidal Rune

Head start: Momentum Rune in slot 1 (area 70–100), Arcane Rune in slot 2 (area 70–100), Prismatic Rune in slot 3 (area 70–100), Tidal Rune in slot 5 (area 70–100)

Verisium Manifestations

5 slots: Rebirth Rune + Lightning Rune + Ward Rune + Cold Rune + Soul Rune

Head start: Lightning Rune in slot 2 (area 70–100), Ward Rune in slot 3 (area 70–100)

Warding Rune of Armature

5 slots: Ward Rune + Volcanic Rune + Bond Rune + Stone Rune + Vision Rune

Head start: Bond Rune in slot 3 (area 70–100), Stone Rune in slot 4 (area 45–100)

Warding Rune of Bodyguards

5 slots: Ward Rune + Protective Rune + Oath Rune + Stone Rune + Prismatic Rune

Head start: Stone Rune in slot 4 (area 45–100)

Warding Rune of Equinox

5 slots: Ward Rune + Tempest Rune + Protective Rune + Stone Rune + Bloodletting Rune

Head start: Stone Rune in slot 4 (area 45–100)

Warding Rune of Hollowing

5 slots: Ward Rune + Lightning Rune + Soul Rune + Stone Rune + Arcane Rune

Head start: Lightning Rune in slot 2 (area 70–100), Stone Rune in slot 4 (area 45–100)

Warding Rune of Obsession

5 slots: Ward Rune + Life Rune + Rage Rune + Stone Rune + Fire Rune

Head start: Stone Rune in slot 4 (area 45–100)

Animus Exchange

6 slots: Arcane Rune + Prismatic Rune + Electrocuting Rune + Ward Rune + Wisdom Rune + Oath Rune

Head start: Ward Rune in slot 4 (area 70–100)

Animus Splinters

6 slots: Bloodletting Rune + Sky Rune + Adaptive Rune + Rage Rune + Soul Rune + Ward Rune

Head start: Sky Rune in slot 2 (area 70–100)

Blazing Flux

6 slots: Fire Rune + Earth Rune + Prismatic Rune + Soul Rune + Rage Rune + Rebirth Rune

Head start: Fire Rune in slot 1 (area 70–100), Prismatic Rune in slot 3 (area 70–100)

Chilling Flux

6 slots: Cold Rune + Cyclonic Rune + Prismatic Rune + Death Rune + Tidal Rune + Moon Rune

Head start: Cold Rune in slot 1 (area 70–100), Prismatic Rune in slot 3 (area 70–100)

Countess Seske's Rune of Archery

6 slots: Time Rune + Tempest Rune + Sky Rune + Wisdom Rune + Ward Rune + Oath Rune

Head start: Time Rune in slot 1 (area 70–100), Sky Rune in slot 3 (area 70–100)

Crackling Flux

6 slots: Lightning Rune + Celestial Rune + Prismatic Rune + Electrocuting Rune + Oath Rune + Tempest Rune

Head start: Lightning Rune in slot 1 (area 70–100), Prismatic Rune in slot 3 (area 70–100)

Divine Orb ×3

6 slots: Death Rune + Soul Rune + Power Rune + Life Rune + Vision Rune + Celestial Rune

Head start: Power Rune in slot 3 (area 65–100)

Explosive Transmutation

6 slots: 2× Volcanic Rune + Sky Rune + Fire Rune + Bond Rune + Ward Rune

Head start: Sky Rune in slot 2 (area 70–100)

Farrul's Rune of the Chase

6 slots: Time Rune + Bloodletting Rune + Cyclonic Rune + Wisdom Rune + Death Rune + Oath Rune

Head start: Time Rune in slot 1 (area 70–100), Cyclonic Rune in slot 3 (area 70–100)

Greater Chaos Orb ×3

6 slots: Oath Rune + Ward Rune + Rage Rune + Volcanic Rune + Opulent Rune + Time Rune

Head start: Oath Rune in slot 1 (area 70–100), Time Rune in slot 6 (area 70–100)

Greater Exalted Orb ×3

6 slots: Oath Rune + Arcane Rune + Bond Rune + Electrocuting Rune + Opulent Rune + Prismatic Rune

Head start: Oath Rune in slot 1 (area 70–100), Bond Rune in slot 3 (area 70–100)

Greater Regal Orb ×3

6 slots: Oath Rune + Cyclonic Rune + Momentum Rune + Moon Rune + Opulent Rune + Bloodletting Rune

Head start: Oath Rune in slot 1 (area 70–100), Momentum Rune in slot 3 (area 70–100), Moon Rune in slot 4 (area 70–100)

Hedgewitch Assandra's Rune of Wisdom

6 slots: Time Rune + Ward Rune + Arcane Rune + Wisdom Rune + Sky Rune + Oath Rune

Head start: Time Rune in slot 1 (area 70–100), Arcane Rune in slot 3 (area 70–100)

Hollow Shell

6 slots: Arcane Rune + Sky Rune + Bloodletting Rune + Prismatic Rune + Life Rune + Ward Rune

Head start: Sky Rune in slot 2 (area 70–100)

Leylines

6 slots: Arcane Rune + Celestial Rune + Rebirth Rune + Ward Rune + Wisdom Rune + Life Rune

Head start: Ward Rune in slot 4 (area 70–100), Life Rune in slot 6 (area 70–100)

Medved's Saga

6 slots: Rage Rune + Vision Rune + Bloodletting Rune + Moon Rune + Time Rune + Wisdom Rune

Head start: Vision Rune in slot 2 (area 70–100), Moon Rune in slot 4 (area 70–100)

Olroth's Saga

6 slots: Tempest Rune + Vision Rune + Time Rune + Celestial Rune + Wisdom Rune + Power Rune

Head start: Vision Rune in slot 2 (area 70–100), Power Rune in slot 6 (area 70–100)

Orb of Annulment

6 slots: Cyclonic Rune + Momentum Rune + Rebirth Rune + Time Rune + Moon Rune + Vision Rune

Head start: Cyclonic Rune in slot 1 (area 70–100), Vision Rune in slot 6 (area 70–100)

Orb of Chance ×2

6 slots: Celestial Rune + Soul Rune + Bloodletting Rune + Rage Rune + Sky Rune + Tempest Rune

Head start: Celestial Rune in slot 1 (area 65–100)

Perfect Chaos Orb

6 slots: Adaptive Rune + 2× Celestial Rune + Oath Rune + Power Rune + Opulent Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Power Rune in slot 4 (area 70–100)

Perfect Exalted Orb

6 slots: Adaptive Rune + Life Rune + Earth Rune + Power Rune + Opulent Rune + Oath Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Power Rune in slot 4 (area 70–100)

Rain of Blades

6 slots: Tempest Rune + Sky Rune + Ward Rune + Arcane Rune + Stone Rune + Rage Rune

Head start: Sky Rune in slot 2 (area 70–100)

Refutation

6 slots: Rage Rune + Prismatic Rune + Stone Rune + Ward Rune + Wisdom Rune + Death Rune

Head start: Ward Rune in slot 4 (area 70–100)

Runic Reprieve

6 slots: Bloodletting Rune + Prismatic Rune + Rebirth Rune + Ward Rune + Wisdom Rune + Soul Rune

Head start: Ward Rune in slot 4 (area 70–100), Soul Rune in slot 6 (area 70–100)

Skyfall

6 slots: Tempest Rune + Celestial Rune + Protective Rune + Ward Rune + Wisdom Rune + Oath Rune

Head start: Ward Rune in slot 4 (area 70–100)

Sovereign Alloy

6 slots: Adaptive Rune + Rebirth Rune + Moon Rune + Toxic Rune + Power Rune + Oath Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Rebirth Rune in slot 2 (area 70–100), Power Rune in slot 5 (area 70–100)

Discover this recipe in Act 2

Thaumaturgic Flux (Level 20)

6 slots: Momentum Rune + Earth Rune + Ward Rune + Stone Rune + Arcane Rune + Oath Rune

Head start: Momentum Rune in slot 1 (area 70–100)

Triskelion Cascade

6 slots: Arcane Rune + Celestial Rune + Stone Rune + Ward Rune + Wisdom Rune + Bond Rune

Head start: Ward Rune in slot 4 (area 70–100)

Uhtred's Saga

6 slots: Ward Rune + Vision Rune + Stone Rune + Arcane Rune + Wisdom Rune + Time Rune

Head start: Vision Rune in slot 2 (area 70–100), Time Rune in slot 6 (area 70–100)

Uncut Skill Gem (Level 20)

6 slots: Momentum Rune + Fire Rune + Death Rune + Wisdom Rune + Protective Rune + Soul Rune

Head start: Momentum Rune in slot 1 (area 70–100), Fire Rune in slot 2 (area 70–100), Soul Rune in slot 6 (area 70–100)

Uncut Spirit Gem (Level 20)

6 slots: Momentum Rune + Arcane Rune + Soul Rune + Wisdom Rune + Prismatic Rune + Oath Rune

Head start: Momentum Rune in slot 1 (area 70–100)

Void Flux

6 slots: Toxic Rune + Time Rune + Adaptive Rune + Soul Rune + Power Rune + Death Rune

Head start: Toxic Rune in slot 1 (area 70–100), Power Rune in slot 5 (area 70–100)

Voltaic Barrier

6 slots: Protective Rune + Sky Rune + Earth Rune + Stone Rune + Death Rune + Ward Rune

Head start: Sky Rune in slot 2 (area 70–100)

Vorana's Saga

6 slots: Moon Rune + Vision Rune + Bond Rune + Time Rune + Wisdom Rune + Toxic Rune

Head start: Vision Rune in slot 2 (area 70–100), Bond Rune in slot 3 (area 70–100)

Wardbound Minions

6 slots: Rebirth Rune + Sky Rune + Toxic Rune + Protective Rune + Oath Rune + Ward Rune

Head start: Sky Rune in slot 2 (area 70–100)

Aldur's Saga

7 slots: Wisdom Rune + Vision Rune + Life Rune + Ward Rune + Power Rune + Arcane Rune + Time Rune

Head start: Wisdom Rune in slot 1 (area 78–100), Vision Rune in slot 2 (area 78–100)

Astrid's Creativity

7 slots: Wisdom Rune + Arcane Rune + Time Rune + Adaptive Rune + Power Rune + Volcanic Rune + Death Rune

Head start: Wisdom Rune in slot 1 (area 78–100), Adaptive Rune in slot 4 (area 70–100)

Betrayal of Aldur

7 slots: Soul Rune + Toxic Rune + Bond Rune + Death Rune + Power Rune + Wisdom Rune + Volcanic Rune

Head start: Soul Rune in slot 1 (area 70–100), Toxic Rune in slot 2 (area 70–100)

Breath of Aldur

7 slots: Soul Rune + Cold Rune + Cyclonic Rune + Tidal Rune + Power Rune + Wisdom Rune + Bond Rune

Head start: Soul Rune in slot 1 (area 70–100), Cold Rune in slot 2 (area 70–100)

Cadigan's Epiphany

7 slots: Wisdom Rune + Sky Rune + Oath Rune + Protective Rune + Power Rune + Soul Rune + Bloodletting Rune

Head start: Wisdom Rune in slot 1 (area 78–100), Soul Rune in slot 6 (area 70–100), Bloodletting Rune in slot 7 (area 70–100)

Celestial Alloy

7 slots: Earth Rune + Rebirth Rune + Celestial Rune + Adaptive Rune + Power Rune + Soul Rune + Cyclonic Rune

Head start: Rebirth Rune in slot 2 (area 70–100), Adaptive Rune in slot 4 (area 70–100), Soul Rune in slot 6 (area 70–100)

Discover this recipe in Act 2

Ire of Aldur

7 slots: Soul Rune + Lightning Rune + Electrocuting Rune + Sky Rune + Power Rune + Wisdom Rune + Celestial Rune

Head start: Soul Rune in slot 1 (area 70–100), Lightning Rune in slot 2 (area 70–100)

Orb of Annulment ×2

7 slots: 2× Cyclonic Rune + Arcane Rune + Vision Rune + Rebirth Rune + Lightning Rune + Power Rune

Head start: Cyclonic Rune in slot 1 (area 70–100), Power Rune in slot 7 (area 70–100)

Passion of Aldur

7 slots: Soul Rune + Fire Rune + Rage Rune + Life Rune + Power Rune + Wisdom Rune + Earth Rune

Head start: Soul Rune in slot 1 (area 70–100), Fire Rune in slot 2 (area 70–100)

Transcendent Alloy

7 slots: Sky Rune + Rebirth Rune + Momentum Rune + Rage Rune + Power Rune + Electrocuting Rune + Death Rune

Head start: Rebirth Rune in slot 2 (area 70–100), Momentum Rune in slot 3 (area 70–100)

Discover this recipe in Act 2

Katla's Gloom

8 slots: Toxic Rune + Bond Rune + Death Rune + Rebirth Rune + Power Rune + Vision Rune + Opulent Rune + Celestial Rune

Head start: Bond Rune in slot 2 (area 70–100), Vision Rune in slot 6 (area 70–100)

Kolr's Hunt

8 slots: Momentum Rune + Bond Rune + Sky Rune + Tempest Rune + Power Rune + Rage Rune + Opulent Rune + Moon Rune

Head start: Bond Rune in slot 2 (area 70–100), Tempest Rune in slot 4 (area 70–100)

Medved's Tending

8 slots: Earth Rune + Bond Rune + Protective Rune + Prismatic Rune + Power Rune + Life Rune + Opulent Rune + Adaptive Rune

Head start: Bond Rune in slot 2 (area 70–100), Life Rune in slot 6 (area 70–100)

Perfect Flux

8 slots: Wisdom Rune + Opulent Rune + Oath Rune + Life Rune + Power Rune + Time Rune + Celestial Rune + Lightning Rune

Head start: Lightning Rune in slot 8 (area 70–100)

Perfect Orb of Augmentation ×3

8 slots: Adaptive Rune + 2× Time Rune + Opulent Rune + Fire Rune + Vision Rune + Bloodletting Rune + Rebirth Rune

Head start: Adaptive Rune in slot 1 (area 70–100), Fire Rune in slot 4 (area 70–100), Vision Rune in slot 6 (area 70–100), Bloodletting Rune in slot 7 (area 70–100), Rebirth Rune in slot 8 (area 70–100)

Perfect Orb of Transmutation ×3