Rune recipes

2 slots: Moon Rune + Vision Rune

Head start: Moon Rune in slot 1 (area 15–100), Vision Rune in slot 2 (area 15–100)

Arcanist's Etcher ×2

2 slots: Lightning Rune + Arcane Rune

Head start: Lightning Rune in slot 1 (area 4–100), Arcane Rune in slot 2 (area 8–100)

Arcanist's Etcher ×4

2 slots: Tidal Rune + Adaptive Rune

Head start: Tidal Rune in slot 1 (area 15–74), Adaptive Rune in slot 2 (area 17–100)

Armourer's Scrap ×2

2 slots: Cold Rune + Stone Rune

Head start: Cold Rune in slot 1 (area 4–100), Stone Rune in slot 2 (area 5–70)

Armourer's Scrap ×4

2 slots: Moon Rune + Adaptive Rune

Head start: Moon Rune in slot 1 (area 15–100), Adaptive Rune in slot 2 (area 17–100)

Artificer's Orb

2 slots: Arcane Rune + Tempest Rune

Head start: Arcane Rune in slot 1 (area 5–100), Tempest Rune in slot 2 (area 4–16)

Artificer's Orb ×2

2 slots: Volcanic Rune + Vision Rune

Head start: Volcanic Rune in slot 1 (area 15–100), Vision Rune in slot 2 (area 15–100)

Blacksmith's Whetstone ×2

2 slots: Fire Rune + Stone Rune

Head start: Fire Rune in slot 1 (area 4–100), Stone Rune in slot 2 (area 5–70)

Blacksmith's Whetstone ×4

2 slots: Rage Rune + Adaptive Rune

Head start: Rage Rune in slot 1 (area 15–74), Adaptive Rune in slot 2 (area 17–100)

Body Rune

2 slots: Protective Rune + Volcanic Rune

Head start: Protective Rune in slot 1 (area 15–77)

Desert Rune

2 slots: Rage Rune + Cyclonic Rune

Head start: Rage Rune in slot 1 (area 15–74), Cyclonic Rune in slot 2 (area 15–77)

Exalted Orb

2 slots: Adaptive Rune + Protective Rune

Head start: Adaptive Rune in slot 1 (area 5–100), Protective Rune in slot 2 (area 12–77)

Gemcutter's Prism

2 slots: Sky Rune + Celestial Rune

Head start: Sky Rune in slot 1 (area 15–100), Celestial Rune in slot 2 (area 25–75)

Glacial Rune

2 slots: Moon Rune + Cyclonic Rune

Head start: Moon Rune in slot 1 (area 15–100), Cyclonic Rune in slot 2 (area 15–77)

Glassblower's Bauble

2 slots: Earth Rune + Celestial Rune

Head start: Earth Rune in slot 1 (area 15–100), Celestial Rune in slot 2 (area 25–75)

Inspiration Rune

2 slots: Electrocuting Rune + Protective Rune

Head start: Protective Rune in slot 2 (area 12–77)

Iron Rune

2 slots: Protective Rune + Cyclonic Rune

Head start: Protective Rune in slot 1 (area 15–77), Cyclonic Rune in slot 2 (area 15–77)

Lesser Adept Rune

2 slots: Cold Rune + Tempest Rune

Head start: Cold Rune in slot 1 (area 4–100), Tempest Rune in slot 2 (area 4–16)

Lesser Body Rune

2 slots: Stone Rune + Electrocuting Rune

Head start: Stone Rune in slot 1 (area 5–100), Electrocuting Rune in slot 2 (area 8–16)

Lesser Charging Rune

2 slots: Cyclonic Rune + Tidal Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Tidal Rune in slot 2 (area 65–100)

Lesser Desert Rune

2 slots: Fire Rune + Momentum Rune

Head start: Fire Rune in slot 1 (area 4–100), Momentum Rune in slot 2 (area 4–16)

Lesser Glacial Rune

2 slots: Cold Rune + Momentum Rune

Head start: Cold Rune in slot 1 (area 4–100), Momentum Rune in slot 2 (area 4–16)

Lesser Inspiration Rune

2 slots: Rebirth Rune + Cold Rune

Head start: Rebirth Rune in slot 1 (area 12–35), Cold Rune in slot 2 (area 5–100)

Lesser Iron Rune

2 slots: Stone Rune + Momentum Rune

Head start: Stone Rune in slot 1 (area 5–100), Momentum Rune in slot 2 (area 4–16)

Lesser Mind Rune

2 slots: Arcane Rune + Electrocuting Rune

Head start: Arcane Rune in slot 1 (area 5–100), Electrocuting Rune in slot 2 (area 8–16)

Lesser Rebirth Rune

2 slots: Rebirth Rune + Moon Rune

Head start: Rebirth Rune in slot 1 (area 12–35), Moon Rune in slot 2 (area 5–100)

Lesser Resolve Rune

2 slots: Lightning Rune + Tempest Rune

Head start: Lightning Rune in slot 1 (area 4–100), Tempest Rune in slot 2 (area 4–16)

Lesser Robust Rune

2 slots: Fire Rune + Tempest Rune

Head start: Fire Rune in slot 1 (area 4–100), Tempest Rune in slot 2 (area 4–16)

Lesser Stone Rune

2 slots: Stone Rune + Cold Rune

Head start: Stone Rune in slot 1 (area 5–100), Cold Rune in slot 2 (area 5–100)

Lesser Storm Rune

2 slots: Lightning Rune + Momentum Rune

Head start: Lightning Rune in slot 1 (area 4–100), Momentum Rune in slot 2 (area 4–16)

Lesser Vision Rune

2 slots: Rebirth Rune + Electrocuting Rune

Head start: Rebirth Rune in slot 1 (area 12–35), Electrocuting Rune in slot 2 (area 8–16)

Lesser Ward Rune

2 slots: Arcane Rune + Moon Rune

Head start: Arcane Rune in slot 1 (area 5–100), Moon Rune in slot 2 (area 5–100)

Mind Rune

2 slots: Volcanic Rune + Fire Rune

Head start: Volcanic Rune in slot 1 (area 15–100), Fire Rune in slot 2 (area 15–100)

Orb of Augmentation

2 slots: Tempest Rune + Lightning Rune

Head start: Tempest Rune in slot 1 (area 1–16), Lightning Rune in slot 2 (area 70–100)

Orb of Augmentation ×2

2 slots: Prismatic Rune + Tidal Rune

Head start: Prismatic Rune in slot 1 (area 12–100), Tidal Rune in slot 2 (area 65–100)

Orb of Transmutation

2 slots: Tempest Rune + Cold Rune

Head start: Tempest Rune in slot 1 (area 1–16), Cold Rune in slot 2 (area 5–100)

Orb of Transmutation ×2

2 slots: Prismatic Rune + Moon Rune

Head start: Prismatic Rune in slot 1 (area 12–100), Moon Rune in slot 2 (area 5–100)

Rebirth Rune

2 slots: Vision Rune + Protective Rune

Head start: Protective Rune in slot 2 (area 12–77)

Regal Orb

2 slots: Adaptive Rune + Moon Rune

Head start: Adaptive Rune in slot 1 (area 5–100), Moon Rune in slot 2 (area 5–100)

Regal Orb ×2

2 slots: Cyclonic Rune + Celestial Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Celestial Rune in slot 2 (area 25–75)

Resolve Rune

2 slots: Tidal Rune + Vision Rune

Head start: Tidal Rune in slot 1 (area 15–74), Vision Rune in slot 2 (area 15–100)

Robust Rune

2 slots: Rage Rune + Vision Rune

Head start: Rage Rune in slot 1 (area 15–74), Vision Rune in slot 2 (area 15–100)

Runic Alloy

2 slots: Adaptive Rune + Rebirth Rune

Head start: Adaptive Rune in slot 1 (area 5–100), Rebirth Rune in slot 2 (area 28–100)

Discover this recipe in Act 2

Stone Rune

2 slots: Protective Rune + Tidal Rune

Head start: Protective Rune in slot 1 (area 15–77), Tidal Rune in slot 2 (area 65–100)

Storm Rune

2 slots: Tidal Rune + Cyclonic Rune

Head start: Tidal Rune in slot 1 (area 15–74), Cyclonic Rune in slot 2 (area 15–77)

Uncut Skill Gem

Gems

2 slots: Momentum Rune + Fire Rune

Head start: Momentum Rune in slot 1, Fire Rune in slot 2 (area 15–100)

Uncut Spirit Gem

Gems

2 slots: Prismatic Rune + Celestial Rune

Head start: Prismatic Rune in slot 1 (area 12–100), Celestial Rune in slot 2 (area 25–75)

Uncut Support Gem

Gems

2 slots: Momentum Rune + Stone Rune

Head start: Momentum Rune in slot 1, Stone Rune in slot 2 (area 5–70)

Vision Rune

2 slots: Vision Rune + Protective Rune

Head start: Protective Rune in slot 2 (area 12–77)

Ward Rune

2 slots: Volcanic Rune + Fire Rune

Head start: Volcanic Rune in slot 1 (area 15–100), Fire Rune in slot 2 (area 15–100)

Adaptive Alloy

3 slots: Earth Rune + Rebirth Rune + Stone Rune

Head start: Earth Rune in slot 1 (area 15–100), Rebirth Rune in slot 2 (area 28–100), Stone Rune in slot 3 (area 30–64)

Discover this recipe in Act 2

Animus Splinters

3 slots: Cold Rune + Sky Rune + Tempest Rune

Head start: Cold Rune in slot 1 (area 70–100), Sky Rune in slot 2 (area 33–100)

Arcanist's Etcher ×6

3 slots: Tidal Rune + Adaptive Rune + Volcanic Rune

Head start: Tidal Rune in slot 1 (area 30–74), Adaptive Rune in slot 2 (area 17–100)

Armourer's Scrap ×6

3 slots: Moon Rune + Adaptive Rune + Cold Rune

Head start: Moon Rune in slot 1 (area 15–100), Adaptive Rune in slot 2 (area 17–100)

Artificer's Orb ×3

3 slots: Stone Rune + Vision Rune + Prismatic Rune

Head start: Stone Rune in slot 1 (area 100–100), Vision Rune in slot 2 (area 30–100), Prismatic Rune in slot 3 (area 55–100)

Bitter Dead

3 slots: Rebirth Rune + Cold Rune + Ward Rune

Head start: Cold Rune in slot 2 (area 65–100), Ward Rune in slot 3 (area 23–100)

Blacksmith's Whetstone ×6

3 slots: Rage Rune + Adaptive Rune + Bloodletting Rune

Head start: Rage Rune in slot 1 (area 30–74), Adaptive Rune in slot 2 (area 17–100), Bloodletting Rune in slot 3 (area 24–100)

Chaos Orb

3 slots: Adaptive Rune + Tidal Rune + Bloodletting Rune

Head start: Adaptive Rune in slot 1 (area 12–100), Tidal Rune in slot 2 (area 65–100), Bloodletting Rune in slot 3 (area 24–100)

Charging Rune

3 slots: Sky Rune + Tidal Rune + Stone Rune

Head start: Sky Rune in slot 1 (area 15–100), Tidal Rune in slot 2 (area 65–100), Stone Rune in slot 3 (area 30–64)

Concussive Runes

3 slots: Cyclonic Rune + Prismatic Rune + Moon Rune

Head start: Cyclonic Rune in slot 1 (area 13–100)

Conductive Runes

3 slots: Cyclonic Rune + Lightning Rune + Vision Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Lightning Rune in slot 2 (area 70–100)

Detonate Living

3 slots: Cyclonic Rune + Cold Rune + Celestial Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Cold Rune in slot 2 (area 65–100)

Eternal March

3 slots: Cyclonic Rune + Cold Rune + Protective Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Cold Rune in slot 2 (area 65–100)

Exalted Orb ×2

3 slots: Adaptive Rune + Arcane Rune + Tidal Rune

Head start: Adaptive Rune in slot 1 (area 12–100), Arcane Rune in slot 2 (area 8–100), Tidal Rune in slot 3 (area 17–100)

Expansive Alloy

3 slots: Volcanic Rune + Rebirth Rune + Tidal Rune

Head start: Volcanic Rune in slot 1 (area 50–100), Rebirth Rune in slot 2 (area 28–100), Tidal Rune in slot 3 (area 17–100)

Discover this recipe in Act 2

Explosive Transmutation

3 slots: Cold Rune + Sky Rune + Fire Rune

Head start: Cold Rune in slot 1 (area 70–100), Sky Rune in slot 2 (area 33–100)

Fist Of Kalguur

3 slots: Bloodletting Rune + Sky Rune + Rage Rune

Head start: Sky Rune in slot 2 (area 33–100)

Fragments Of The Past

3 slots: Cyclonic Rune + Tidal Rune + Lightning Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Tidal Rune in slot 2 (area 65–100)

Frostflame Nova

3 slots: Cyclonic Rune + Cold Rune + Fire Rune

Head start: Cyclonic Rune in slot 1 (area 13–100), Cold Rune in slot 2 (area 65–100)

Gemcutter's Prism ×2

3 slots: Prismatic Rune + Celestial Rune + Bond Rune

Head start: Prismatic Rune in slot 1 (area 25–100), Bond Rune in slot 3 (area 70–100)

Glassblower's Bauble ×2

3 slots: Prismatic Rune + Toxic Rune + Tidal Rune

Head start: Prismatic Rune in slot 1 (area 25–100), Toxic Rune in slot 2 (area 65–100), Tidal Rune in slot 3 (area 17–100)

Greater Adept Rune

3 slots: Moon Rune + Vision Rune + Lightning Rune

Head start: Moon Rune in slot 1 (area 15–100), Vision Rune in slot 2 (area 30–100)

Greater Body Rune

3 slots: Protective Rune + Volcanic Rune + Stone Rune

Head start: Protective Rune in slot 1 (area 30–77), Stone Rune in slot 3 (area 30–64)

Greater Charging Rune

3 slots: Protective Rune + Ward Rune + Fire Rune

Head start: Protective Rune in slot 1 (area 30–77), Ward Rune in slot 2 (area 30–100)

Greater Desert Rune

3 slots: Rage Rune + Cyclonic Rune + Earth Rune

Head start: Rage Rune in slot 1 (area 30–74), Cyclonic Rune in slot 2 (area 30–77)

Greater Glacial Rune

3 slots: Moon Rune + Cyclonic Rune + Rage Rune

Head start: Moon Rune in slot 1 (area 15–100), Cyclonic Rune in slot 2 (area 30–77)

Greater Inspiration Rune

3 slots: Electrocuting Rune + Protective Rune + Rebirth Rune

Head start: Protective Rune in slot 2 (area 12–77), Rebirth Rune in slot 3 (area 30–77)

Greater Iron Rune

3 slots: Protective Rune + Cyclonic Rune + Celestial Rune

Head start: Protective Rune in slot 1 (area 30–77), Cyclonic Rune in slot 2 (area 30–77)

Greater Mind Rune

3 slots: Volcanic Rune + Fire Rune + Rebirth Rune

Head start: Volcanic Rune in slot 1 (area 50–100), Fire Rune in slot 2 (area 70–100), Rebirth Rune in slot 3 (area 30–77)

Greater Orb of Augmentation

3 slots: Momentum Rune + Life Rune + Tempest Rune

Head start: Momentum Rune in slot 1 (area 44–100)

Greater Orb of Transmutation

3 slots: Momentum Rune + Life Rune + Cold Rune

Head start: Momentum Rune in slot 1 (area 44–100)

Greater Rebirth Rune

3 slots: Vision Rune + Protective Rune + Rebirth Rune

Head start: Protective Rune in slot 2 (area 12–77), Rebirth Rune in slot 3 (area 30–77)

Greater Resolve Rune

3 slots: Tidal Rune + Vision Rune + Earth Rune

Head start: Tidal Rune in slot 1 (area 30–74), Vision Rune in slot 2 (area 30–100)

Greater Robust Rune

3 slots: 2× Rage Rune + Vision Rune

Head start: Rage Rune in slot 1 (area 30–74), Vision Rune in slot 2 (area 30–100)

Greater Stone Rune

3 slots: Protective Rune + Tidal Rune + Celestial Rune

Head start: Protective Rune in slot 1 (area 30–77), Tidal Rune in slot 2 (area 65–100)

Greater Storm Rune

3 slots: Tidal Rune + Cyclonic Rune + Vision Rune

Head start: Tidal Rune in slot 1 (area 30–74), Cyclonic Rune in slot 2 (area 30–77)

Greater Vision Rune

3 slots: Vision Rune + Protective Rune + Cold Rune

Head start: Protective Rune in slot 2 (area 12–77)

Greater Ward Rune

3 slots: Protective Rune + Ward Rune + Lightning Rune

Head start: Protective Rune in slot 1 (area 30–77), Ward Rune in slot 2 (area 30–100)

Grim Pillars

3 slots: Volcanic Rune + Cold Rune + Ward Rune

Head start: Volcanic Rune in slot 1 (area 50–100), Cold Rune in slot 2 (area 65–100), Ward Rune in slot 3 (area 23–100)

Hollow Shell

3 slots: Arcane Rune + Sky Rune + Earth Rune

Head start: Arcane Rune in slot 1 (area 15–100), Sky Rune in slot 2 (area 33–100)

Lesser Jeweller's Orb

3 slots: Prismatic Rune + Arcane Rune + Cyclonic Rune

Head start: Prismatic Rune in slot 1 (area 25–100), Arcane Rune in slot 2 (area 8–100), Cyclonic Rune in slot 3 (area 70–100)

Orb of Alchemy

3 slots: Adaptive Rune + Rebirth Rune + Prismatic Rune

Head start: Adaptive Rune in slot 1 (area 12–100), Rebirth Rune in slot 2 (area 28–100), Prismatic Rune in slot 3 (area 55–100)

Powered by Verisium

3 slots: Arcane Rune + Earth Rune + Ward Rune

Head start: Arcane Rune in slot 1 (area 15–100), Ward Rune in slot 3 (area 23–100)

Protective Alloy

3 slots: Sky Rune + Rebirth Rune + Bloodletting Rune

Head start: Sky Rune in slot 1 (area 15–100), Rebirth Rune in slot 2 (area 28–100), Bloodletting Rune in slot 3 (area 24–100)

Discover this recipe in Act 2

Rain of Blades

3 slots: Arcane Rune + Sky Rune + Tempest Rune

Head start: Arcane Rune in slot 1 (area 15–100), Sky Rune in slot 2 (area 33–100)

Regal Orb ×3

3 slots: Earth Rune + Arcane Rune + Tidal Rune

Head start: Earth Rune in slot 1 (area 15–100), Arcane Rune in slot 2 (area 8–100), Tidal Rune in slot 3 (area 17–100)

Remnants of Kalguur

3 slots: Sky Rune + Tidal Rune + Ward Rune

Head start: Sky Rune in slot 1 (area 15–100), Tidal Rune in slot 2 (area 65–100), Ward Rune in slot 3 (area 23–100)

Repulsion

3 slots: Cyclonic Rune + Earth Rune + Protective Rune

Head start: Cyclonic Rune in slot 1 (area 13–100)

Runeforged Blades

3 slots: Volcanic Rune + Electrocuting Rune + Ward Rune

Head start: Volcanic Rune in slot 1 (area 50–100), Ward Rune in slot 3 (area 23–100)

Runic Alloy ×2